The thermo-oxidative processes of cyclopentanone, cyclohexanone, their alkyl derivatives, spiro acetals were investigated by method thermochemicalluminescence (TCL) at non-isothermal heating. It is shown that the intensive TCL occurs in compounds with mobile hydrogen atoms and the efficient generation of free radicals. It is suggested that these compounds can be offered as biological additives to increase the therapeutic properties of various oils and vegetable oils