It is established that at reaction of arylsulfonylhydrazides with 1,2-and 1,3-dipolarofiles getarylsulfamides with 65-80% yield form. It was found that monosulfonylhydrazides with acetyl acetone, benzoacetoaceticethyl ester and 4-oxymethylphenylmethylenemalonodinitrile form pirazolone-and pirazol derivatives of sulfamides. N-substituted derivatives of sulfanylhydrazide prepared by N-alkylation of sulfamide natrium by chloroacetonitrile is also sintone for obtaining of getarylsulfamides. This compound forms with benzoine-, pirazoline-, with acetyl acetone-, pyridazin-, but with acetoaceticethyl ester-, pyridazine derivatives of sulfamides. Investigations of antimikrobic properties of synthesized getarylsulfamides showed that 1-(4-methylphenylsulfonyl)-, 2-(4-aminopirazolines and 1-phenyl-3-(4-methylphenylsulfonyl)-pirazolone-3