SYNTHESIS OF OPTICALLY ACTIVE DIETHYL (S)-3-(HYDROXYMETHYL)-3,6-DIHYDROPYRIDAZINE-1,2-DICARBOXYLATE

F.N.Akhundova, M.J.Alves, M.M.Qurbanova

The optically active diethyl (S)-3-(hydroxymethyl)-3,6-dihydropyridazine-1,2-dicarboxylate were synthesized based on asymmetric Diels-Alder reaction in the presence of (S)-BINOL chiral catalyst, the structure was approved by NMR, Mass, Infrared spectroscopies, and specific rotation was determined by AUTOPOL III polarimeter.

Keywords : Diels–Alder reaction, (S)-BINOL chiral catalyst, glycosidase, optical purity

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№2 2026

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