The synthesized S-enantiomer of the crown ether was used as an adsorbent to separate the racemic mixture of L-alanine ether of phenamine into individual diastereomers by column chromatography. Chromatographic separation occurred due to the formation of complexes of different stability between diastereomers and optically selective adsorbents on a ²host-guest² principle. The separated diastereo­mers were converted into enantiomers by hydrolysis. The structure and optical activity of the synthesized crown ether and separated enantiomers were investigated by physicochemical methods

doi.org/10.32737/0005-2531-2021-3-59-62