ISSN 0005-2531 (Print) ISSN 2522-1841 (Online)
SYNTHESIS, CONVERSION AND ANTIMICROBIAL ACTIVITY OF DERIVATIVES OF 2-HYDROXY-1-HALOIDPHENOXYETHERS OF NONANOL-2
S.A.Mammadov, A.A.Mahmudova, G.G.Mammadova, V.S.Hasanov, N.P.Ladokhina, L.F.Zeynalova

Reactivity of hydroxyl group in 1-haloid-phenoxy-2-hydroxynonanes to nucleophilic substitution with acetoxymethylchloride was studied. It was found that regardless of the nature of haloids and their position in aryloxy radical the yields of acetoxymethyl ethers makes nearly 70% that  proves high reactivity of hydroxyl group. Indeed, during the reaction with isocyanates phenoxynonanol-2 forms urethanes with yield 69–70%. Initial synthon was prepared by the reaction of 1-bromine-nonanol-2 with substituted phenols. Study of synthesized polyethers and urethanes as antimicrobial additives to lubricating oils gave positive results. It was determined that urethanes exhibit stronger antimicrobial effect than polyethers

doi.org/10.32737/0005-2531-2020-1-59-65 

Keywords : phenoxyethers, urethanes, polyethers, acetoxymethyl, antimicrobial additives
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